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Ribonucleases as potential modalities in anticancer therapy
Antitumor ribonucleases are small (10–28 kDa) basic proteins. They were found among members of both, ribonuclease A and T1 superfamilies. Their cytotoxic properties are conferred by enzymatic activity, i.e., the ability to catalyze cleavages of phosphodiester bonds in RNA. They bind to negatively ch...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784098/ https://ncbi.nlm.nih.gov/pubmed/19825371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.06.067 |
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