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Ribonucleases as potential modalities in anticancer therapy

Antitumor ribonucleases are small (10–28 kDa) basic proteins. They were found among members of both, ribonuclease A and T1 superfamilies. Their cytotoxic properties are conferred by enzymatic activity, i.e., the ability to catalyze cleavages of phosphodiester bonds in RNA. They bind to negatively ch...

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Autores principales: Ardelt, Wojciech, Ardelt, Barbara, Darzynkiewicz, Zbigniew
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784098/
https://ncbi.nlm.nih.gov/pubmed/19825371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.06.067
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