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Cytostatic and Cytotoxic Properties of Amphinase: A Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes

Onconase (Onc) is a novel amphibian cytotoxic ribonuclease with antitumor activity and is currently in a confirmatory phase III clinical trial for the treatment of malignant mesothelioma. It was recently reported that Rana pipiens oocytes contain still another ribonuclease, named Amphinase (Amph). A...

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Bibliographic Details
Main Authors: Ardelt, Barbara, Ardelt, Wojciech, Pozarowski, Piotr, Kunicki, Jan, Shogen, Kuslima, Darzynkiewicz, Zbigniew
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586934/
https://ncbi.nlm.nih.gov/pubmed/18073526
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