E1A signaling to p53 involves the p19(ARF) tumor suppressor
The adenovirus E1A oncogene activates p53 through a signaling pathway involving the retinoblastoma protein and the tumor suppressor p19(ARF). The ability of E1A to induce p53 and its transcriptional targets is severely compromised in ARF-null cells, which remain resistant to apoptosis following seru...
Uloženo v:
| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9694807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.15.2434 |
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