The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling

Smad proteins are critical signal transducers downstream of the receptors of the transforming growth factor-β (TGFβ) superfamily. On phosphorylation and activation by the active TGFβ receptor complex, Smad2 and Smad3 form hetero-oligomers with Smad4 and translocate into the nucleus, where they inter...

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Autors principals: Luo, Kunxin, Stroschein, Shannon L., Wang, Wei, Chen, Dan, Martens, Eric, Zhou, Sharleen, Zhou, Qiang
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316985/
https://ncbi.nlm.nih.gov/pubmed/10485843
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