The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling

Smad proteins are critical signal transducers downstream of the receptors of the transforming growth factor-β (TGFβ) superfamily. On phosphorylation and activation by the active TGFβ receptor complex, Smad2 and Smad3 form hetero-oligomers with Smad4 and translocate into the nucleus, where they inter...

Full description

Saved in:
Bibliographic Details
Main Authors: Luo, Kunxin, Stroschein, Shannon L., Wang, Wei, Chen, Dan, Martens, Eric, Zhou, Sharleen, Zhou, Qiang
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1999
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316985/
https://ncbi.nlm.nih.gov/pubmed/10485843
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items