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The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling

Smad proteins are critical signal transducers downstream of the receptors of the transforming growth factor-β (TGFβ) superfamily. On phosphorylation and activation by the active TGFβ receptor complex, Smad2 and Smad3 form hetero-oligomers with Smad4 and translocate into the nucleus, where they inter...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Luo, Kunxin, Stroschein, Shannon L., Wang, Wei, Chen, Dan, Martens, Eric, Zhou, Sharleen, Zhou, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10485843/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.17.2196
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