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The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signaling
Smad proteins are critical signal transducers downstream of the receptors of the transforming growth factor-β (TGFβ) superfamily. On phosphorylation and activation by the active TGFβ receptor complex, Smad2 and Smad3 form hetero-oligomers with Smad4 and translocate into the nucleus, where they inter...
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| Yayımlandı: | Genes Dev |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10485843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.17.2196 |
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