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TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
Transforming growth factor-β (TGF-β) is a potent inhibitor of skeletal muscle differentiation, but the molecular mechanism and signaling events that lead to this inhibition are poorly characterized. Here we show that the TGF-β intracellular effector Smad3, but not Smad2, mediates the inhibition of m...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312830/ https://ncbi.nlm.nih.gov/pubmed/11711431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.925901 |
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