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TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

Transforming growth factor-β (TGF-β) is a potent inhibitor of skeletal muscle differentiation, but the molecular mechanism and signaling events that lead to this inhibition are poorly characterized. Here we show that the TGF-β intracellular effector Smad3, but not Smad2, mediates the inhibition of m...

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Hlavní autoři: Liu, Dong, Black, Brian L., Derynck, Rik
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC312830/
https://ncbi.nlm.nih.gov/pubmed/11711431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.925901
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