TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
Transforming growth factor-β (TGF-β) is a potent inhibitor of skeletal muscle differentiation, but the molecular mechanism and signaling events that lead to this inhibition are poorly characterized. Here we show that the TGF-β intracellular effector Smad3, but not Smad2, mediates the inhibition of m...
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| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11711431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.925901 |
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