Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and -independent mechanisms

PIK3CA gain-of-function mutations are a common oncogenic event in human malignancy(1–4), making PI3K an attractive target for cancer therapy. Despite the great promise of targeted therapy, resistance often develops, resulting in treatment failure. To elucidate mechanisms of resistance to PI3K-target...

詳細記述

保存先:
書誌詳細
主要な著者: Liu, Pixu, Cheng, Hailing, Santiago, Stephanie, Raeder, Maria, Zhang, Fan, Isabella, Adam, Yang, Janet, Semaan, Derek J., Chen, Changzhong, Fox, Edward A., Gray, Nathanael S., Monahan, John, Schlegel, Robert, Beroukhim, Rameen, Mills, Gordon B., Zhao, Jean J.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169724/
https://ncbi.nlm.nih.gov/pubmed/21822287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2402
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料