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Oncogenic Mutations of PIK3CA in Human Cancers

The involvement of the PIK3CA gene product p110a, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K), in human cancer has been suggested for over 15 years, and support for this proposal had been provided by both genetic and functional studies, including most recently the discovery of comm...

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Detalhes bibliográficos
Main Authors: Samuels, Yardena, Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164550/
https://ncbi.nlm.nih.gov/pubmed/20535651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2010_68
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