Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
Our recent work has shown that activation of the Ras/Raf/ERK pathway extends the half-life of the Myc protein and thus enhances the accumulation of Myc activity. We have extended these observations by investigating two N-terminal phosphorylation sites in Myc, Thr 58 and Ser 62, which are known to be...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11018017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.836800 |
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