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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability

Our recent work has shown that activation of the Ras/Raf/ERK pathway extends the half-life of the Myc protein and thus enhances the accumulation of Myc activity. We have extended these observations by investigating two N-terminal phosphorylation sites in Myc, Thr 58 and Ser 62, which are known to be...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sears, Rosalie, Nuckolls, Faison, Haura, Eric, Taya, Yoichi, Tamai, Katsuyuki, Nevins, Joseph R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC316970/
https://ncbi.nlm.nih.gov/pubmed/11018017
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