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CD4(+)CD25(+)Foxp3(+) regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletion

CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells are generated during thymocyte development and play a crucial role in preventing the immune system from attacking the body's cells and tissues. However, how the formation of these cells is directed by T-cell receptor (TCR) recognition of self-pept...

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Bibliografiset tiedot
Päätekijät: Cozzo Picca, Cristina, Simons, Donald M., Oh, Soyoung, Aitken, Malinda, Perng, Olivia A., Mergenthaler, Christina, Kropf, Elizabeth, Erikson, Jan, Caton, Andrew J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169143/
https://ncbi.nlm.nih.gov/pubmed/21873239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103810108
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