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How specificity for self-peptides shapes the development and function of regulatory T cells
The cataclysmic disease that develops in mice and humans lacking CD4(+) T cells expressing the transcription factor Foxp3 has provided abundant evidence that Foxp3(+)CD4(+) Tregs are required to suppress a latent autoreactivity of the immune system. There is also evidence for the existence of tissue...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Leukocyte Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996893/ https://ncbi.nlm.nih.gov/pubmed/20495071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0310183 |
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