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Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis()
CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) are required to restrain the immune system from mounting an autoaggressive systemic inflammatory response, but why their activity can prevent (or allow) organ-specific autoimmunity remains poorly understood. We have examined how TCR specificity contri...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331886/ https://ncbi.nlm.nih.gov/pubmed/22450809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103598 |
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