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Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) regulatory T cell formation
We have analyzed the relationship between CD4(+)CD8(−) (CD4SP) thymocyte deletion and CD4SPFoxp3(+) Treg formation using mice in which signals transmitted by the TCR have been attenuated by mutation of one of three tyrosine residues (Y145) of the adapter protein Src homology 2 domain-containing leuk...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959276/ https://ncbi.nlm.nih.gov/pubmed/24307208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343767 |
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