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Thymocyte deletion can bias regulatory T cell formation toward low abundance self-peptide
Autoreactive CD4(+) T cells can undergo deletion and/or become CD25(+)Foxp3(+) Treg cells as they develop intrathymically, but how these alternative developmental fates are specified based on interactions with self-peptide(s) is not understood. We show here that thymocytes expressing an autoreactive...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829603/ https://ncbi.nlm.nih.gov/pubmed/19768697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939709 |
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