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Distinct modes of antigen presentation promote the formation, differentiation and activity of Foxp3(+) regulatory T cells in vivo

How the formation and activity of CD4(+)Foxp3(+) regulatory T cells (Tregs) is shaped by TCR recognition of the diverse array of peptide:MHC complexes that can be generated from self- and/or foreign Ags in vivo remains poorly understood. We show that a self-peptide with low (but not high) stimulator...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Weissler, Katherine A., Garcia, Victoria, Kropf, Elizabeth, Aitken, Malinda, Bedoya, Felipe, Wolf, Amaya I., Erikson, Jan, Caton, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390510/
https://ncbi.nlm.nih.gov/pubmed/25780041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402960
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