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The Degree of CD4(+) T Cell Autoreactivity Determines Cellular Pathways Underlying Inflammatory Arthritis

Although therapies targeting distinct cellular pathways (e.g. anti-cytokine versus anti-B cell therapy) have been found to be an effective strategy for at least some patients with inflammatory arthritis, the mechanisms that determine which pathways promote arthritis development are poorly understood...

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Detalhes bibliográficos
Main Authors: Perng, Olivia A., Aitken, Malinda, Rankin, Andrew L., Garcia, Victoria, Kropf, Elizabeth, Erikson, Jan, Garlick, David S., Caton, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974175/
https://ncbi.nlm.nih.gov/pubmed/24591372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302528
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