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G Protein coupled Receptor Specificity for C3a and Compound 48/80-induced degranulation in human mast cells: Roles of Mas-related genes MrgX1 and MrgX2

Although human mast cells express G protein coupled receptors for the anaphylatoxin C3a, previous studies indicated that C3a causes mast cell degranulation, at least in part, via a C3a receptor-independent mechanism similar to that proposed for polycationic molecules such as compound 48/80. The purp...

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Detalhes bibliográficos
Main Authors: Kashem, Sakeen W., Subramanian, Hariharan, Collington, Sarah J., Magotti, Paola, Lambris, John D., Ali, Hydar
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169012/
https://ncbi.nlm.nih.gov/pubmed/21741965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.06.027
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