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MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells

LL-37 is the sole antimicrobial peptide of human cathelicidin comprising 37 amino acids, which is expressed mainly in epithelial cells and neutrophils, and activates mast cells. In the present study, in order to elucidate the mechanism of mast cell activation by LL-37, the associations between the i...

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Detalles Bibliográficos
Publicado en:Mol Med Rep
Main Authors: Murakami, Taisuke, Suzuki, Kaori, Niyonsaba, Francois, Tada, Hiroyuki, Reich, Johannes, Tamura, Hiroshi, Nagaoka, Isao
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236315/
https://ncbi.nlm.nih.gov/pubmed/30280189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9532
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