MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells

LL-37 is the sole antimicrobial peptide of human cathelicidin comprising 37 amino acids, which is expressed mainly in epithelial cells and neutrophils, and activates mast cells. In the present study, in order to elucidate the mechanism of mast cell activation by LL-37, the associations between the i...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Murakami, Taisuke, Suzuki, Kaori, Niyonsaba, Francois, Tada, Hiroyuki, Reich, Johannes, Tamura, Hiroshi, Nagaoka, Isao
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236315/
https://ncbi.nlm.nih.gov/pubmed/30280189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9532
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