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Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice

LL-37 is the only known member of the cathelicidin family of antimicrobial peptides in humans. In addition to its broad spectrum of antimicrobial activities, LL-37 can modulate various inflammatory reactions. We previously revealed that LL-37 suppresses the LPS/ATP-induced pyroptosis of macrophages...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Hu, Zhongshuang, Murakami, Taisuke, Suzuki, Kaori, Tamura, Hiroshi, Reich, Johannes, Kuwahara-Arai, Kyoko, Iba, Toshiaki, Nagaoka, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888352/
https://ncbi.nlm.nih.gov/pubmed/26746575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxv113
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