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Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils

Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice. Ectosomes, microvesicles released from neutrophil...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Innate Immun
Prif Awduron: Kumagai, Yumi, Murakami, Taisuke, Kuwahara-Arai, Iba, Toshiaki, Reich, Johannes, Nagaoka, Isao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556193/
https://ncbi.nlm.nih.gov/pubmed/32600088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425920936754
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