The mast cell degranulator compound 48/80 directly activates neurons.

BACKGROUND: Compound 48/80 is widely used in animal and tissue models as a "selective" mast cell activator. With this study we demonstrate that compound 48/80 also directly activates enteric neurons and visceral afferents. METHODOLOGY/PRINCIPAL FINDINGS: We used in vivo recordings from ext...

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Detaylı Bibliyografya
Asıl Yazarlar: Michael Schemann, Eva Maria Kugler, Sabine Buhner, Christopher Eastwood, Jemma Donovan, Wen Jiang, David Grundy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2012-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3525567?pdf=render
Etiketler: Etiketle
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