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TNF-alpha neutralizing antibody blocks thermal sensitivity induced by compound 48/80-provoked mast cell degranulation

Background: Neuro-inflammatory circuits in the tissue regulate the complex pathophysiology of pain. Protective nociceptive pain serves as an early warning system against noxious environmental stimuli. Tissue-resident mast cells orchestrate the increased thermal sensitivity following injection of bas...

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Detalhes bibliográficos
Main Authors: Chatterjea, Devavani, Paredes, Luisa, Martinov, Tijana, Balsells, Evelyn, Allen, Juliann, Sykes, Akilah, Ashbaugh, Alyssa
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869523/
https://ncbi.nlm.nih.gov/pubmed/24555087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-178.v2
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