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β-defensins activate human mast cells via Mas-related Gene-X2 (MrgX2)

Human β-defensins (hBDs) stimulate degranulation in rat peritoneal mast cells in vitro and cause increased vascular permeability in rats in vivo. Here, we sought to determine if hBDs activate murine and human mast cells and to delineate the mechanisms of their regulation. hBD2 and hBD3 did not induc...

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Detalhes bibliográficos
Main Authors: Subramanian, Hariharan, Gupta, Kshitij, Lee, Donguk, Bayir, Arzu K, Ahn, Harry, Ali, Hydar
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691353/
https://ncbi.nlm.nih.gov/pubmed/23698749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300023
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