PML is induced by oncogenic ras and promotes premature senescence

Oncogenic ras provokes a senescent-like arrest in human diploid fibroblasts involving the Rb and p53 tumor suppressor pathways. To further characterize this response, we compared gene expression patterns between ras-arrested and quiescent IMR90 fibroblasts. One of the genes up-regulated during ras-i...

詳細記述

書誌詳細

出版年:	Genes Dev
主要な著者:	Ferbeyre, Gerardo, de Stanchina, Elisa, Querido, Emmanuelle, Baptiste, Nicole, Prives, Carol, Lowe, Scott W.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cold Spring Harbor Laboratory Press 2000
主題:	Research Paper
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10950866/
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