A requirement for NF-κB activation in Bcr–Abl-mediated transformation

Bcr–Abl is a chimeric oncoprotein that is strongly implicated in acute lymphoblastic (ALL) and chronic myelogenous leukemias (CML). This deregulated tyrosine kinase selectively causes hematopoietic disorders resembling human leukemias in animal models and transforms fibroblasts and hematopoietic cel...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Reuther, Julie Y., Reuther, Gary W., Cortez, David, Pendergast, Ann Marie, Baldwin, Albert S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1998
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.968
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