A requirement for NF-κB activation in Bcr–Abl-mediated transformation

Bcr–Abl is a chimeric oncoprotein that is strongly implicated in acute lymphoblastic (ALL) and chronic myelogenous leukemias (CML). This deregulated tyrosine kinase selectively causes hematopoietic disorders resembling human leukemias in animal models and transforms fibroblasts and hematopoietic cel...

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Main Authors: Reuther, Julie Y., Reuther, Gary W., Cortez, David, Pendergast, Ann Marie, Baldwin, Albert S.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC316671/
https://ncbi.nlm.nih.gov/pubmed/9531535
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