A requirement for NF-κB activation in Bcr–Abl-mediated transformation
Bcr–Abl is a chimeric oncoprotein that is strongly implicated in acute lymphoblastic (ALL) and chronic myelogenous leukemias (CML). This deregulated tyrosine kinase selectively causes hematopoietic disorders resembling human leukemias in animal models and transforms fibroblasts and hematopoietic cel...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316671/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9531535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.7.968 |
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