Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human β-globin locus
We have investigated the mechanism, structural correlates, and cis-acting elements involved in chromatin opening and gene activation, using the human β-globin locus as a model. Full transcriptional activity of the human β-globin locus requires the locus control region (LCR), composed of a series of...
Guardat en:
| Publicat a: | Genes Dev |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10783166/ |
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