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The murine β-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes
Locus control regions (LCRs) are defined by their ability to confer high-level tissue-specific expression to linked genes in transgenic assays. Previously, we reported that, at its native site, the murine β-globin LCR is required for high-level β-globin gene expression, but is not required to initia...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58747/ https://ncbi.nlm.nih.gov/pubmed/11553791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201394698 |
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