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The murine β-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes

Locus control regions (LCRs) are defined by their ability to confer high-level tissue-specific expression to linked genes in transgenic assays. Previously, we reported that, at its native site, the murine β-globin LCR is required for high-level β-globin gene expression, but is not required to initia...

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Bibliografske podrobnosti
Main Authors: Schübeler, Dirk, Groudine, Mark, Bender, M. A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC58747/
https://ncbi.nlm.nih.gov/pubmed/11553791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201394698
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