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Histone hyperacetylation within the β-globin locus is context-dependent and precedes high-level gene expression

Active gene promoters are associated with covalent histone modifications, such as hyperacetylation, which can modulate chromatin structure and stabilize binding of transcription factors that recognize these modifications. At the β-globin locus and several other loci, however, histone hyperacetylatio...

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Detalhes bibliográficos
Main Authors: Fromm, George, de Vries, Christina, Byron, Rachel, Fields, Jennifer, Fiering, Steven, Groudine, Mark, Bender, M. A., Palis, James, Bulger, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765682/
https://ncbi.nlm.nih.gov/pubmed/19690338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210690
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