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A transient definitive erythroid lineage with unique regulation of the β-globin locus in the mammalian embryo

A transient erythromyeloid wave of definitive hematopoietic progenitors (erythroid/myeloid progenitors [EMPs]) emerges in the yolk sac beginning at embryonic day 8.25 (E8.25) and colonizes the liver by E10.5, before adult-repopulating hematopoietic stem cells. At E11.5, we observe all maturational s...

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Detalhes bibliográficos
Main Authors: McGrath, Kathleen E., Frame, Jenna M., Fromm, George J., Koniski, Anne D., Kingsley, Paul D., Little, Jane, Bulger, Michael, Palis, James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099576/
https://ncbi.nlm.nih.gov/pubmed/21378272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-325357
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