Histone hyperacetylation within the β-globin locus is context-dependent and precedes high-level gene expression

Active gene promoters are associated with covalent histone modifications, such as hyperacetylation, which can modulate chromatin structure and stabilize binding of transcription factors that recognize these modifications. At the β-globin locus and several other loci, however, histone hyperacetylatio...

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Main Authors: Fromm, George, de Vries, Christina, Byron, Rachel, Fields, Jennifer, Fiering, Steven, Groudine, Mark, Bender, M. A., Palis, James, Bulger, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Red Cells, Iron, and Erythropoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765682/
https://ncbi.nlm.nih.gov/pubmed/19690338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210690
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