Histone hyperacetylation within the β-globin locus is context-dependent and precedes high-level gene expression

Active gene promoters are associated with covalent histone modifications, such as hyperacetylation, which can modulate chromatin structure and stabilize binding of transcription factors that recognize these modifications. At the β-globin locus and several other loci, however, histone hyperacetylatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Fromm, George, de Vries, Christina, Byron, Rachel, Fields, Jennifer, Fiering, Steven, Groudine, Mark, Bender, M. A., Palis, James, Bulger, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2009
Ämnen:
Red Cells, Iron, and Erythropoiesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765682/
https://ncbi.nlm.nih.gov/pubmed/19690338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210690
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