Histone hyperacetylation within the β-globin locus is context-dependent and precedes high-level gene expression

Active gene promoters are associated with covalent histone modifications, such as hyperacetylation, which can modulate chromatin structure and stabilize binding of transcription factors that recognize these modifications. At the β-globin locus and several other loci, however, histone hyperacetylatio...

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Главные авторы: Fromm, George, de Vries, Christina, Byron, Rachel, Fields, Jennifer, Fiering, Steven, Groudine, Mark, Bender, M. A., Palis, James, Bulger, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2009
Предметы:
Red Cells, Iron, and Erythropoiesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765682/
https://ncbi.nlm.nih.gov/pubmed/19690338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210690
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