The Locus Control Region Is Necessary for Gene Expression in the Human β-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid Cells

Studies in many systems have led to the model that the human β-globin locus control region (LCR) regulates the transcription, chromatin structure, and replication properties of the β-globin locus. However the precise mechanisms of this regulation are unknown. We have developed strategies to use homo...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Reik, Andreas, Telling, Agnes, Zitnik, Galynn, Cimbora, Daniel, Epner, Elliot, Groudine, Mark
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.5992
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