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Loss of Cytoplasmic CDK1 Predicts Poor Survival in Human Lung Cancer and Confers Chemotherapeutic Resistance

The dismal lethality of lung cancer is due to late stage at diagnosis and inherent therapeutic resistance. The incorporation of targeted therapies has modestly improved clinical outcomes, but the identification of new targets could further improve clinical outcomes by guiding stratification of poor-...

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Autors principals: Zhang, Chunyu, Elkahloun, Abdel G., Robertson, Matthew, Gills, Joell J., Tsurutani, Junji, Shih, Joanna H., Fukuoka, Junya, Hollander, M. Christine, Harris, Curtis C., Travis, William D., Jen, Jin, Dennis, Phillip A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161069/
https://ncbi.nlm.nih.gov/pubmed/21887332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023849
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