Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer

Non-small cell lung cancer (NSCLC) accounts for 80–85% of lung cancer cases, and almost half of newly diagnosed patients have metastatic disease. Pemetrexed is a widely used drug for NSCLC and inhibits several folate-dependent enzymes including thymidylate synthase (TS). Increased expression of TS c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kawabata, Shigeru, Chiang, Chun-Te, Tsurutani, Junji, Shiga, Hideaki, Arwood, Matthew L., Komiya, Takefumi, Gills, Joell J., Memmott, Regan M., Dennis, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011583/
https://ncbi.nlm.nih.gov/pubmed/24658085
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados