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High nuclear/cytoplasmic ratio of Cdk1 expression predicts poor prognosis in colorectal cancer patients

BACKGROUND: Cdk1 (cyclin-dependent kinase 1) is critical regulator of the G2-M checkpoint. Cyclin-dependent kinase pathways are considered possible targets for cancer treatment; however, the prognostic role of Cdk1 in colorectal cancer is still controversial. Therefore, we attempted to determine the...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Sung, Wen-Wei, Lin, Yueh-Min, Wu, Pei-Ru, Yen, Hsu-Heng, Lai, Hung-Wen, Su, Tzu-Cheng, Huang, Ren-Hung, Wen, Chun-Kai, Chen, Chia-Yu, Chen, Chih-Jung, Yeh, Kun-Tu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302138/
https://ncbi.nlm.nih.gov/pubmed/25511643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-951
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