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Perifosine: Update on a Novel Akt Inhibitor
The PI3K/Akt/mTOR pathway is aberrantly active in most human cancers and contributes to cell growth, proliferation, and survival. Akt is a nodal regulator of cellular survival pathways and an attractive target in cancer therapy. Many inhibitors of Akt are being developed. Perifosine is an oral Akt i...
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| Publicado no: | Curr Oncol Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957247/ https://ncbi.nlm.nih.gov/pubmed/19216841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-009-0016-4 |
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