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In Vitro and In Vivo Inhibition of Neuroblastoma Tumor Cell Growth by AKT Inhibitor Perifosine

BACKGROUND: Activated AKT is a marker of decreased event-free or overall survival in neuroblastoma (NB) patients. The aim of this study was to investigate the effect of perifosine, a nontoxic AKT inhibitor, as a single agent on NB cell growth in vitro and in vivo. METHODS: Four human NB cell lines (...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Zhijie, Tan, Fei, Liewehr, David J., Steinberg, Seth M., Thiele, Carol J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879416/
https://ncbi.nlm.nih.gov/pubmed/20463309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq125
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