Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance.

The dismal lethality of lung cancer is due to late stage at diagnosis and inherent therapeutic resistance. The incorporation of targeted therapies has modestly improved clinical outcomes, but the identification of new targets could further improve clinical outcomes by guiding stratification of poor-...

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Hauptverfasser: Chunyu Zhang, Abdel G Elkahloun, Matthew Robertson, Joell J Gills, Junji Tsurutani, Joanna H Shih, Junya Fukuoka, M Christine Hollander, Curtis C Harris, William D Travis, Jin Jen, Phillip A Dennis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3161069?pdf=render
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