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Expression signatures of the lipid-based Akt inhibitors phosphatidylinositol ether lipid analogues (PIAs) in NSCLC cells

Activation of the serine/threonine kinase Akt contributes to the formation, maintenance, and therapeutic resistance of cancer, which is driving development of compounds that inhibit Akt. Phosphatidylinositol ether lipid analogues (PIAs) are analogues of the products of PI3K that inhibit Akt activati...

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Autors principals: Zhang, Chunyu, Elkahloun, Abdel G., Liao, Hongling, Delaney, Shannon, Saber, Barbara, Morrow, Betsy, Gills, Joell J., Hollander, M. Christine, Prendergast, George C., Dennis, Phillip A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132820/
https://ncbi.nlm.nih.gov/pubmed/21551261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1028
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