Expression signatures of the lipid-based Akt inhibitors phosphatidylinositol ether lipid analogues (PIAs) in NSCLC cells

Activation of the serine/threonine kinase Akt contributes to the formation, maintenance, and therapeutic resistance of cancer, which is driving development of compounds that inhibit Akt. Phosphatidylinositol ether lipid analogues (PIAs) are analogues of the products of PI3K that inhibit Akt activati...

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Detalhes bibliográficos
Main Authors: Zhang, Chunyu, Elkahloun, Abdel G., Liao, Hongling, Delaney, Shannon, Saber, Barbara, Morrow, Betsy, Gills, Joell J., Hollander, M. Christine, Prendergast, George C., Dennis, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132820/
https://ncbi.nlm.nih.gov/pubmed/21551261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1028
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