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Induction of HLA-DP4-restricted anti-Survivin Th1 and Th2 responses using an artificial antigen-presenting cell
PURPOSE: In previous cancer vaccine clinical trials targeting Survivin, induction of specific CD8(+) T cell responses did not consistently lead to clinical responses. Considering the critical role of CD4(+) T cell help in generating anti-tumor immunity, integration of anti-Survivin CD4(+) T cell res...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156899/ https://ncbi.nlm.nih.gov/pubmed/21705450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3083 |
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