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Transgenic expression of human signal regulatory protein alpha in Rag2(−/−)γ(c)(−/−) mice improves engraftment of human hematopoietic cells in humanized mice
Transplantation of human hematopoietic stem cells into severely immunocompromised newborn mice allows the development of a human hematopoietic and immune system in vivo. NOD/scid/γ(c)(−/−) (NSG) and BALB/c Rag2(−/−)γ(c)(−/−) mice are the most commonly used mouse strains for this purpose and a number...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156175/ https://ncbi.nlm.nih.gov/pubmed/21788509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109769108 |
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